A Comparative Study of Cytomorphological Patterns of Lymph Node Aspirates in Paediatric and Adult Populations
Published: October 1, 2020 | DOI: https://doi.org/10.7860/JCDR/2020/44982.14072
M Dedeepya, AS Ramaswamy, BN Kumarguru, M Udaya Kumar
1. Postgraduate Student, Department of Pathology, PES Institute of Medical Sciences and Research, Kuppam, Andhra Pradesh, India.
2. Professor and Head, Department of Pathology, PES Institute of Medical Sciences and Research, Kuppam, Andhra Pradesh, India.
3. Associate Professor, Department of Pathology, PES Institute of Medical Sciences and Research, Kuppam, Andhra Pradesh, India.
4. Professor, Department of Pathology, PES Institute of Medical Sciences and Research, Kuppam, Andhra Pradesh, India.
Correspondence
Dr. BN Kumarguru,
“Sri”nivasa, No: 204, 9th Cross, BEML Layout, I Stage, Basaveshwaranagare, Bangalore-560079, Karnataka, India.
E-mail: kumarguru1978@yahoo.com
Introduction: Lymphadenopathy is one of the most common clinical presentations of patients. Lymph node is a commonly aspirated organ for diagnostic purposes. Fine Needle Aspiration Cytology (FNAC) of lymph node has become an integral part of initial diagnosis and management.
Aim: To compare the cytomorphological patterns of the lymph node lesions in the paediatric population with that of the adult population and to correlate with the available histopathological diagnosis.
Materials and Methods: It was a retrospective observational study of lymph node lesions conducted at a rural tertiary care referral institute, PES Institute of Medical Sciences and Research (PESIMSR), Kuppam, Andhra Pradesh, India, from January 2017 to June 2018 for a period of 18 months. Cytology smears were retrieved, reviewed and analysed. Cytological diagnosis was compared with available histopathological diagnosis and concordance was calculated. Chi-square test was the statistical tool used to analyse the data in the study.
Results: Two hundred and seventy four cases were analysed. Adult population constituted 225 cases (82.12%). Paediatric population constituted 49 cases (17.88%). Reactive lymphadenitis was the commonest pattern in both the groups. Chronic lymphoproliferative lesions {4 cases (1.7%)} constituted the least common lesion in adults and mycobacterial lymphadenitis {1 case (2.04%)} constituted the least common lesion in paediatric population.
Conclusion: Distribution of cytological patterns of lymph node lesions in paediatric and adult populations are different and are found to be statistically significant. Cytological evaluation of lymph node lesions has a high diagnostic efficacy for the diagnosis of neoplastic lesions.
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